BDBM50392792 CHEMBL2151322::US8486966, 7

SMILES CC(C)Oc1cc(n[nH]1)-n1cnc2ccc(N[C@@H](CO)c3ccc(F)cn3)nc12

InChI Key InChIKey=CEDQYWYBSMPQAF-HNNXBMFYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392792   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50392792(CHEMBL2151322 | US8486966, 7)Copy SMILESCopy InChI

Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

US Patent

LigandBDBM50392792(CHEMBL2151322 | US8486966, 7)Copy SMILESCopy InChI

Affinity DataIC50:  3nMT: 2°CAssay Description:JAK2 and Trk A kinase activity was determined by measuring the kinase's ability to phoshorylate synthetic tyrosine residues within a generic poly...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI