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BDBM50392919 CHEMBL2152217

SMILES: Cc1c(Cl)cccc1S(=O)(=O)N1CCC[C@@H](C1)C(=O)N[C@H]1C[C@H]2CC[C@]1(C)C2(C)C

InChI Key: InChIKey=MHUVSJCDOKWREY-OITUCODZSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50392919   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM50392919
PNG
(CHEMBL2152217)
Show SMILES Cc1c(Cl)cccc1S(=O)(=O)N1CCC[C@@H](C1)C(=O)N[C@H]1C[C@H]2CC[C@]1(C)C2(C)C
Show InChI InChI=1S/C23H33ClN2O3S/c1-15-18(24)8-5-9-19(15)30(28,29)26-12-6-7-16(14-26)21(27)25-20-13-17-10-11-23(20,4)22(17,2)3/h5,8-9,16-17,20H,6-7,10-14H2,1-4H3,(H,25,27)/t16-,17+,20-,23-/m0/s1
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Similars

Article
PubMed
n/an/a 0.400n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human 11betaHSD1 by scintillation proximity assay


ACS Med Chem Lett 3: 793-798 (2012)


Article DOI: 10.1021/ml300144n
BindingDB Entry DOI: 10.7270/Q2K938NZ
More data for this
Ligand-Target Pair