BDBM50393040 CHEMBL2152710
SMILES CC(C)(C)C(=O)NCc1ccc(Br)c(c1)C(=O)Nc1ncc[nH]1
InChI Key InChIKey=HEFWIGRGDVKSTG-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50393040
Affinity DataIC50: 180nMAssay Description:Inhibition of human mPGES-1More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of human mPGES-1 assessed as production of PGE2 by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 607nMAssay Description:Inhibition of mPGES-1 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 198nMAssay Description:Inhibition of human microsomal PGES1 expressed in 293E cells by LC/MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 284nMAssay Description:Inhibition of mPGES1 in rhIL-1beta-stimulated human A549 cells assessed as PGE2 level treated for 18 hrs after 30 mins pre-incubation with rhIL-1beta...More data for this Ligand-Target Pair
Affinity DataIC50: 607nMAssay Description:Inhibition of mPGES1 in LPS-induced human whole blood assessed as suppression of PGE2 response after 20 to 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of mPGES-1 in IL-1beta-stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 formation incubated for 15 mins using...More data for this Ligand-Target Pair