BDBM50393110 CHEMBL2153260

SMILES Nc1nc2c(nccc2[nH]1)-c1ccco1

InChI Key InChIKey=MJNLEGDDXDONRO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50393110   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Macquarie University

Curated by ChEMBL
LigandPNGBDBM50393110(CHEMBL2153260)
Affinity DataIC50:  6.19E+4nMAssay Description:Inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Macquarie University

Curated by ChEMBL
LigandPNGBDBM50393110(CHEMBL2153260)
Affinity DataIC50:  1.59E+4nMAssay Description:Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Macquarie University

Curated by ChEMBL
LigandPNGBDBM50393110(CHEMBL2153260)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of human recombinant CDK5/p25 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed