BDBM50393456 CHEMBL2159690
SMILES CCNC(=O)OCC[C@@H]1OCC[C@@]2([C@H]1COc1c(F)ccc(F)c21)S(=O)(=O)c1ccc(Cl)cc1
InChI Key InChIKey=CBBFOFOYZAQDFL-NVVBAYIOSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50393456
Affinity DataIC50: 48nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair