BDBM50393832 CHEMBL2159739
SMILES CCn1c(C)c(C(O)=O)c(c1-c1ccc(Cl)cc1)-c1cccc(c1)N1CCN(CC1)c1ccc(NS(=O)(=O)c2ccc(N[C@H](CCN(C)C)CSc3ccccc3)c(c2)[N+]([O-])=O)cc1
InChI Key InChIKey=PYQJFMBPKZZCMB-KXQOOQHDSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50393832
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human N-terminal His8-tagged Mcl1 expressed in Escherichia coli BL21(DE3) assessed as inhibition of Fluorescein-labeled BID binding aft...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity to BCL2 (unknown origin) after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Binding affinity to BCL-XL (unknown origin) after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human N-terminal His8-tagged Bcl-XL expressed in Escherichia coli BL21(DE3) assessed as inhibition of Fluorescein-labeled BAK binding a...More data for this Ligand-Target Pair