BDBM50394739 CHEMBL2165827

SMILES OCCNCCN1CCCc2cc(NC(=N)c3cccs3)ccc12

InChI Key InChIKey=NPCGRBLSVKLOQW-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50394739   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394739(CHEMBL2165827)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells at -80 mV holding potential assessed as reduction in tail current amplitude by conventional patch c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394739(CHEMBL2165827)
Affinity DataIC50:  115nMAssay Description:Inhibition of human nNOS expressed in Sf9 cells assessed as reduction in conversion of [3H]L-arginine to [3H]L-citrulline preincubated for 15 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394739(CHEMBL2165827)
Affinity DataIC50:  3.29E+4nMAssay Description:Inhibition of human eNOS expressed in Sf9 cells assessed as reduction in conversion of [3H]L-arginine to [3H]L-citrulline preincubated for 15 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394739(CHEMBL2165827)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of human recombinant iNOS expressed in Sf9 cells assessed as reduction in conversion of [3H]L-arginine to [3H]L-citrulline preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed