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BDBM50396033 CHEMBL2169982

SMILES: COc1cc2CCN(C(=O)Nc3cc(cc(c3)C(F)(F)F)-c3cccnc3)c2cc1C(F)(F)F

InChI Key: InChIKey=YAZJLXFAUHRWKL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50396033   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 2C (5-HT2C)


(Homo sapiens (human))
BDBM50396033
PNG
(CHEMBL2169982)
Show SMILES COc1cc2CCN(C(=O)Nc3cc(cc(c3)C(F)(F)F)-c3cccnc3)c2cc1C(F)(F)F
Show InChI InChI=1S/C23H17F6N3O2/c1-34-20-9-13-4-6-32(19(13)11-18(20)23(27,28)29)21(33)31-17-8-15(14-3-2-5-30-12-14)7-16(10-17)22(24,25)26/h2-3,5,7-12H,4,6H2,1H3,(H,31,33)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 10n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...


ACS Med Chem Lett 3: 373-377 (2012)


Article DOI: 10.1021/ml300008j
BindingDB Entry DOI: 10.7270/Q2PZ59X6
More data for this
Ligand-Target Pair