BDBM50396090 CHEMBL2170758

SMILES Oc1cccc(c1)C(=O)Nc1nc2ccc(O)cc2s1

InChI Key InChIKey=XGCKLYXJNJVNJZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50396090   

Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50396090(CHEMBL2170758)
Affinity DataIC50:  245nMAssay Description:Inhibition of 17beta-HSD1 in human T47D cells using unlabelled and [2,4,6,7-3H]estrone as substrate preincubated for 30 mins prior to substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50396090(CHEMBL2170758)
Affinity DataIC50:  243nMAssay Description:Inhibition of human placenta 17beta-HSD1 cytosolic fraction using unlabelled and [2,4,6,7-3H]estrone as substrate after 10 mins by HPLC analysis in p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50396090(CHEMBL2170758)
Affinity DataIC50:  9.26E+3nMAssay Description:Inhibition of human placenta 17beta-HSD2 microsomal fraction using unlabelled and [2,4,6,7-3H]estradiol as substrate after 20 mins by HPLC analysis i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed