BDBM50396178 CHEMBL2172014

SMILES CN(CC(=O)N(Cc1ccc(cc1)C1CCN(CC1)c1ccc(cc1)C#N)c1ccc(C(O)=O)c(O)c1)S(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=JEAOHUCEWQKGOA-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396178   

TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50396178(CHEMBL2172014)
Affinity DataKi:  1.87E+4nMAssay Description:Inhibition of STAT3 SH2 domain assessed as inhibition of STAT3 SH2-phosphotyrosine interaction after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50396178(CHEMBL2172014)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed