BDBM50396262 CHEMBL2172322

SMILES OC[C@H]1CC[C@H](CC1)n1c(NC(=O)c2cccc(c2)S(=O)(=O)NCC=C)nc2cc(CN3CCCCC3)ccc12

InChI Key InChIKey=LWJAHJMKAARBCO-WZJNIGMMSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50396262   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396262(CHEMBL2172322)
Affinity DataIC50:  48nMAssay Description:Inhibition of ALK Tyr1604 phosphorylation by cell based assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396262(CHEMBL2172322)
Affinity DataIC50:  5.92E+3nMAssay Description:Inhibition of c-Met enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396262(CHEMBL2172322)
Affinity DataIC50:  5nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair