BDBM50397343 CHEMBL2170135

SMILES OC1=NC(=S)C(S1)=Cc1ccc(cc1)C([O-])=O

InChI Key InChIKey=QYCZDJALECNZGD-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50397343   

TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50397343(CHEMBL2170135)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of human recombinant Tdp1 assessed as conversion of 14-mer 5'-32P-labeled 3'-phosphotyrosyl DNA substrate N14Y to 14-mer 5'-32P-labeled 3'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50397343(CHEMBL2170135)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human recombinant Tdp1 expressed in Tdp1 knockout chicken DT40 cells using 5'-32P-labeled 5'-GATCTAAAAGACTT-pY-3' as substrate after 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed