BDBM50397699 CHEMBL2181915
SMILES CC(C)(C)Cc1cnc2OC3(CCC3)C[C@H](NC[C@@H](O)[C@H](Cc3cccc(c3)-c3nccs3)NC(=O)[C@H]3CCCO3)c2c1
InChI Key InChIKey=DZIXUQJNRCUJQW-QUAHOIDUSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50397699
Affinity DataIC50: 11nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta 40 production after overnight incubati...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human recombinant BACE1 using Glu-Ile-Asp-Leu-Met-Val-Leu-Asp as substrate incubated for 60 mins prior to substrate addition measured a...More data for this Ligand-Target Pair