BDBM50397714 CHEMBL2181900
SMILES COCC(=O)N[C@@H](Cc1cccc(-c2nccs2)c1F)[C@H](O)CN[C@H]1CC2(CCC2)Oc2ncc(CC(C)(C)C)cc12
InChI Key InChIKey=IVHJMOJHRRFXHT-KKUQBAQOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50397714
Affinity DataIC50: 71nMAssay Description:Inhibition of human recombinant BACE1 using Glu-Ile-Asp-Leu-Met-Val-Leu-Asp as substrate incubated for 60 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta 40 production after overnight incubati...More data for this Ligand-Target Pair