BDBM50397836 CHEMBL2179073

SMILES CCN(CC)CCOc1cccc(Nc2nc(cc(n2)-c2ccc(Cl)cc2)-c2ccc(Cl)cc2)c1

InChI Key InChIKey=YFDRYCDHDMZGBD-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50397836   

TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50397836(CHEMBL2179073)
Affinity DataKd:  1.02E+5nMAssay Description:Binding affinity to human recombinant bitinylated receptor for advanced glycation end product expressed in Escherichia coli DE3 after 1 min by surfac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50397836(CHEMBL2179073)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of biotinylated human RAGE/amyloid beta interaction incubated for 120 mins by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50397836(CHEMBL2179073)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibition of amyloid beta binding to biotin-labeled human RAGE domain V after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50397836(CHEMBL2179073)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibition of human recombinant biotinylated receptor for advanced glycation end product expressed in Escherichia coli DE3 assessed as inhibition of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed