BDBM50398059 CHEMBL2181932

SMILES Cc1c(cn(CCO)c1-c1ccccc1C(F)(F)F)C(=O)Nc1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=NOSNHVJANRODGR-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50398059   

TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398059(CHEMBL2181932)
Affinity DataIC50:  2.40nMAssay Description:Antagonist activity at mineralocorticoid receptorMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398059(CHEMBL2181932)
Affinity DataIC50:  9.40nMAssay Description:Antagonist activity at Gal4-fused human MR LBD (671 to 984 residues) expressed in African Green Monkey CV-1 cells assessed as inhibition of aldostero...More data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398059(CHEMBL2181932)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at Gal4-fused human MR LBD (671 to 984 residues) expressed in African Green Monkey CV-1 cells assessed as inhibition of aldostero...More data for this Ligand-Target Pair