BDBM50398612 CHEMBL2177468
SMILES C[C@H]1C[C@@]2(CN(C)S(=O)(=O)N2c2cccc(F)c2)CCN1Cc1ccc(O)c(Cl)c1
InChI Key InChIKey=OPALZHQMUWJZMW-YCRPNKLZSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50398612
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant BACE1 using K(biotin)RGLTTRPGSGLTNIKTEEISEVNLDAEFRHDSGA as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of BACE1-mediated sAPPbeta production in human H4 cells expressing APP 695 after 18 hrs by ELISAMore data for this Ligand-Target Pair