BDBM50399285 CHEMBL2180820::US9102622, 14.3

SMILES Oc1ccccc1CCCCCCCS(F)(=O)=O

InChI Key InChIKey=PBWDFIOEUOQKKZ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50399285   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of Connecticut

US Patent
LigandPNGBDBM50399285(CHEMBL2180820 | US9102622, 14.3)
Affinity DataKi:  13nM ΔG°:  -11.2kcal/mole IC50:  54nMT: 2°CAssay Description:All compound solutions are made to a concentration of 10 mM in DMSO. To test the stability of the compounds in enzyme assay conditions, 25 nmoles of ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50399285(CHEMBL2180820 | US9102622, 14.3)
Affinity DataIC50:  56.1nMAssay Description:Inhibition of recombinant human hexahistidine-tagged MGL expressed in Escherichia coli using AHMMCE as substrate after 15 mins by medium throughput f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed