BDBM50400209 CHEMBL2181023

SMILES COC(=O)[C@@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)N(C)C(=O)[C@@H](N)C(C)C

InChI Key InChIKey=KQBGZTOQVQFMJZ-JTIJPRSZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50400209   

TargetBeta-secretase 1(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400209(CHEMBL2181023)
Affinity DataIC50:  10nMAssay Description:Inhibition of BACE1 expressed in CHO 2B7 cells expressing wild type APP695 assessed as reduction in Abeta40/Abeta42 levels incubated for 16 hrs by sa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400209(CHEMBL2181023)
Affinity DataIC50:  17nMAssay Description:Inhibition of cathepsin D by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin E(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400209(CHEMBL2181023)
Affinity DataIC50:  58nMAssay Description:Inhibition of cathepsin E by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400209(CHEMBL2181023)
Affinity DataIC50:  211nMAssay Description:Inhibition of BACE1 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed