BDBM50400214 CHEMBL2181022

SMILES COC(=O)[C@@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)N(C)C(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C

InChI Key InChIKey=NXDIWJUYMKBICN-QDBLDGTHSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50400214   

TargetBeta-secretase 1(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400214(CHEMBL2181022)
Affinity DataIC50:  54nMAssay Description:Inhibition of BACE1 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400214(CHEMBL2181022)
Affinity DataIC50:  54nMAssay Description:Inhibition of BACE1 (unknown origin) after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin E(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400214(CHEMBL2181022)
Affinity DataIC50:  0.724nMAssay Description:Inhibition of cathepsin E by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400214(CHEMBL2181022)
Affinity DataIC50:  54nMAssay Description:Inhibition of BACE1 (unknown origin) using Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2 as substrate incubated for 120 mins by fl...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCathepsin D(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50400214(CHEMBL2181022)
Affinity DataIC50:  0.0783nMAssay Description:Inhibition of recombinant human liver Cathepsin D using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate incubated for 120 mi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCathepsin E(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50400214(CHEMBL2181022)
Affinity DataIC50:  0.724nMAssay Description:Inhibition of Cathepsin E (unknown origin) using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate incubated for 120 mins by f...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCathepsin D(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50400214(CHEMBL2181022)
Affinity DataIC50:  0.0783nMAssay Description:Inhibition of cathepsin D by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed