BDBM50400221 CHEMBL2181015
SMILES COC(=O)[C@@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)N(C)C(=O)[C@@H](NC(=O)[C@H](C)O)C(C)C
InChI Key InChIKey=WFMVRFNXMBGKEW-HVGQEOIXSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50400221
Affinity DataIC50: 189nMAssay Description:Inhibition of BACE1 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of BACE1 (unknown origin) using peptide substrate by time-course measurement-based fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant cathepsin E using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate preincubated for 15 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human liver cathepsin D using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate preincubated for 15 mins followe...More data for this Ligand-Target Pair
Affinity DataIC50: 189nMAssay Description:Inhibition of BACE1 (unknown origin) using Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2 as substrate incubated for 120 mins by fl...More data for this Ligand-Target Pair
Affinity DataIC50: 182nMAssay Description:Inhibition of cathepsin D by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 182nMAssay Description:Inhibition of recombinant human liver Cathepsin D using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate incubated for 120 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of Cathepsin E (unknown origin) using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate incubated for 120 mins by f...More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of cathepsin E by fluorescence assayMore data for this Ligand-Target Pair