BDBM50400221 CHEMBL2181015

SMILES COC(=O)[C@@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)N(C)C(=O)[C@@H](NC(=O)[C@H](C)O)C(C)C

InChI Key InChIKey=WFMVRFNXMBGKEW-HVGQEOIXSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50400221   

TargetBeta-secretase 1(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50400221(CHEMBL2181015)
Affinity DataIC50:  189nMAssay Description:Inhibition of BACE1 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50400221(CHEMBL2181015)
Affinity DataIC50:  80nMAssay Description:Inhibition of BACE1 (unknown origin) using peptide substrate by time-course measurement-based fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin E(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50400221(CHEMBL2181015)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant cathepsin E using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate preincubated for 15 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50400221(CHEMBL2181015)
Affinity DataIC50:  50nMAssay Description:Inhibition of human liver cathepsin D using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate preincubated for 15 mins followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50400221(CHEMBL2181015)
Affinity DataIC50:  189nMAssay Description:Inhibition of BACE1 (unknown origin) using Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2 as substrate incubated for 120 mins by fl...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCathepsin D(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50400221(CHEMBL2181015)
Affinity DataIC50:  182nMAssay Description:Inhibition of cathepsin D by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50400221(CHEMBL2181015)
Affinity DataIC50:  182nMAssay Description:Inhibition of recombinant human liver Cathepsin D using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate incubated for 120 mi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCathepsin E(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50400221(CHEMBL2181015)
Affinity DataIC50:  66nMAssay Description:Inhibition of Cathepsin E (unknown origin) using Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys-(Dnp)-D-Arg-NH2 as substrate incubated for 120 mins by f...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCathepsin E(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50400221(CHEMBL2181015)
Affinity DataIC50:  66nMAssay Description:Inhibition of cathepsin E by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed