BDBM50400737 CHEMBL2203538

SMILES CCN1C(=S)NC(=O)\C(=C/c2c[nH]c3ccccc23)C1=O

InChI Key InChIKey=IJQSAWQFPLEJDM-YRNVUSSQSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50400737   

TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
TBA

Curated by ChEMBL

LigandBDBM50400737(CHEMBL2203538)Copy SMILESCopy InChI

Affinity DataIC50:  5.59E+4nMAssay Description:Inhibition of SIRT5 using ZK(suc)A substrate after 1 hr by homogeneous fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
TBA

Curated by ChEMBL

LigandBDBM50400737(CHEMBL2203538)Copy SMILESCopy InChI

Affinity DataIC50:  8.93E+4nMAssay Description:Inhibition of recombinant SIRT1 using ZMAL substrate after 4 hrs by homogeneous fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI