BDBM50400889 CHEMBL2204357
SMILES Cc1cccc(Sc2ccccc2N2CCNCC2)c1C
InChI Key InChIKey=IFZNYQPTDBKBSE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50400889
Affinity DataKi: 29nMAssay Description:Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Displacement of [3H]5-carboxamidotryptamine to human 5HT1A expressed in HEK293 cells by filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using resorufin benzyl ether after 30 mins by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human recombinant CYP2D6 using 3-[2-(N,N-diethyl-N-methylamino)ethyl]-7-methoxy- 4-methylcoumarin after 45 mins by fluorescence spectro...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9 using dibenzylfluorescein after 45 mins by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxy-3-cyanocoumarin after 28 mins by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of SERT-mediated [3H]5HT uptake in rat synaptosomes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of DAT-mediated [3H]DA in rat synaptomsomes by scintillation countingMore data for this Ligand-Target Pair