BDBM50401385 CHEMBL2206447

SMILES COc1cc(F)cc(F)c1C1CCN(CC1)c1ccn2c(CC3CC3)nnc2c1Cl

InChI Key InChIKey=XLLJAPMXDNKGQJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50401385   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50401385(CHEMBL2206447)
Affinity DataEC50:  6.90nMAssay Description:Agonist activity at human mGLuR2 expressed in CHO cell membrane assessed as [32S]GTPgammaS after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50401385(CHEMBL2206447)
Affinity DataIC50:  5.60nMAssay Description:Displacement of [3H]JNJ-40068782 from human mGLuR2 expressed in CHO cell membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed