BDBM50402990 CHEMBL2207427

SMILES CC(C)NC(=O)c1cc2cccc(NC(=O)Nc3cc(nn3-c3ccc(C)cc3)C(C)(C)C)c2[nH]1

InChI Key InChIKey=WGABQSVUYBMTBW-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50402990   

TargetFocal adhesion kinase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402990(CHEMBL2207427)
Affinity DataIC50:  7.86E+3nMAssay Description:Inhibition of FAK after 2hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402990(CHEMBL2207427)
Affinity DataIC50:  78nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 2-beta(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402990(CHEMBL2207427)
Affinity DataIC50:  530nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair