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BDBM50404870 CHEMBL350836

SMILES: OC(=O)c1ccc2nc3ccc(O)cc3c(=O)n2c1

InChI Key: InChIKey=XGVHFMCIAPRAIT-UHFFFAOYSA-N

Data: 2 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50404870   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alkaline phosphatase placental-like


(Homo sapiens (Human))
BDBM50404870
PNG
(CHEMBL350836)
Show SMILES OC(=O)c1ccc2nc3ccc(O)cc3c(=O)n2c1
Show InChI InChI=1S/C13H8N2O4/c16-8-2-3-10-9(5-8)12(17)15-6-7(13(18)19)1-4-11(15)14-10/h1-6,16H,(H,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.80E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
50% inhibition of human placental alkaline phosphatase in the presence of 10 mM p-nitrophenyl phosphate as substrate


J Med Chem 25: 742-5 (1982)


Article DOI: 10.1021/jm00348a025
BindingDB Entry DOI: 10.7270/Q20G3MBH
More data for this
Ligand-Target Pair
Alkaline phosphatase tissue-nonspecific


(Rattus norvegicus)
BDBM50404870
PNG
(CHEMBL350836)
Show SMILES OC(=O)c1ccc2nc3ccc(O)cc3c(=O)n2c1
Show InChI InChI=1S/C13H8N2O4/c16-8-2-3-10-9(5-8)12(17)15-6-7(13(18)19)1-4-11(15)14-10/h1-6,16H,(H,18,19)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.40E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition of human leukocyte alkaline phosphatase in the presence of 10 mM p-nitrophenyl phosphate as substrate


J Med Chem 25: 742-5 (1982)


Article DOI: 10.1021/jm00348a025
BindingDB Entry DOI: 10.7270/Q20G3MBH
More data for this
Ligand-Target Pair