BDBM50405043 1-(4-(Benzyloxy)phenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine hydrochloride (B2-01)::CHEMBL7191
SMILES CC1(C)N=C(N)N=C(N)N1c1ccc(OCc2ccccc2)cc1
InChI Key InChIKey=HUTXUOTUXFTILM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50405043
Affinity DataKi: 30nMAssay Description:Inhibitory activity against isolated chicken liver dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKi: 117nMAssay Description:Inhibitory activity against human lymphoblastoid cell (WIL2) dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKi: 6.46E+3nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 1.44E+4nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute Of Chemical Technology
Institute Of Chemical Technology
Affinity DataIC50: 32nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair