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BDBM50406653 CHEMBL313060

SMILES: COc1ccc(NC(=O)NCCCOc2cccc(CN3CCCCC3)c2)c(OC)c1

InChI Key: InChIKey=URRSRVUDGCPBSR-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406653   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406653
PNG
(CHEMBL313060)
Show SMILES COc1ccc(NC(=O)NCCCOc2cccc(CN3CCCCC3)c2)c(OC)c1
Show InChI InChI=1S/C24H33N3O4/c1-29-20-10-11-22(23(17-20)30-2)26-24(28)25-12-7-15-31-21-9-6-8-19(16-21)18-27-13-4-3-5-14-27/h6,8-11,16-17H,3-5,7,12-15,18H2,1-2H3,(H2,25,26,28)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 2.24E+3n/an/an/an/an/a



Kyorin Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.


J Med Chem 35: 2446-51 (1992)


Article DOI: 10.1021/jm00091a012
BindingDB Entry DOI: 10.7270/Q2V9898T
More data for this
Ligand-Target Pair