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BDBM50406662 CHEMBL312601

SMILES: FC(F)(F)c1ccc(NC(=O)NCCCOc2cccc(CN3CCCCC3)c2)cc1

InChI Key: InChIKey=VAHSNCINYMWAGT-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406662   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50406662
PNG
(CHEMBL312601)
Show SMILES FC(F)(F)c1ccc(NC(=O)NCCCOc2cccc(CN3CCCCC3)c2)cc1
Show InChI InChI=1S/C23H28F3N3O2/c24-23(25,26)19-8-10-20(11-9-19)28-22(30)27-12-5-15-31-21-7-4-6-18(16-21)17-29-13-2-1-3-14-29/h4,6-11,16H,1-3,5,12-15,17H2,(H2,27,28,30)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.70E+3n/an/an/an/an/a



Kyorin Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.


J Med Chem 35: 2446-51 (1992)


Article DOI: 10.1021/jm00091a012
BindingDB Entry DOI: 10.7270/Q2V9898T
More data for this
Ligand-Target Pair