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BDBM50407518 ISOPROTERENOL::L-ISOPRENALINE::LEVISOPRENALINE

SMILES: CC(C)NC[C@@H](O)c1ccc(O)c(O)c1

InChI Key: InChIKey=JWZZKOKVBUJMES-LLVKDONJSA-N

Data: 3 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50407518   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adrenergic receptor beta


(Rattus norvegicus)
BDBM50407518
PNG
(ISOPROTERENOL | L-ISOPRENALINE | LEVISOPRENALINE)
Show SMILES CC(C)NC[C@@H](O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3/t11-/m1/s1
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KEGG

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PubMed
n/an/an/an/a 6.30E+4n/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Activity for beta 3-adrenoceptor was assessed from effect on stimulation of lipolysis in rat adipocytes.


J Med Chem 38: 3681-716 (1995)

More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50407518
PNG
(ISOPROTERENOL | L-ISOPRENALINE | LEVISOPRENALINE)
Show SMILES CC(C)NC[C@@H](O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3/t11-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
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PubMed
n/an/an/an/a 1.70E+3n/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Activity for Beta-2 adrenergic receptor was assessed from effect on relaxation of guinea pig trachea.


J Med Chem 38: 3681-716 (1995)

More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50407518
PNG
(ISOPROTERENOL | L-ISOPRENALINE | LEVISOPRENALINE)
Show SMILES CC(C)NC[C@@H](O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3/t11-/m1/s1
GoogleScholar
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PC cid
PC sid
UniChem

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PubMed
n/an/an/an/a 2.20E+3n/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Activity for Beta-1 adrenergic receptor was assessed from ability to stimulate contractions in isolated guinea pig atrium.


J Med Chem 38: 3681-716 (1995)

More data for this
Ligand-Target Pair