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BDBM50408850 CHEMBL348875

SMILES: CN1C[C@H](COC(=O)C2CCCCC2)C=C2[C@H]1Cc1c[nH]c3cccc2c13

InChI Key: InChIKey=NHINDOWVGVTFBF-QVKFZJNVSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50408850   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50408850
PNG
(CHEMBL348875)
Show SMILES CN1C[C@H](COC(=O)C2CCCCC2)C=C2[C@H]1Cc1c[nH]c3cccc2c13
Show InChI InChI=1S/C23H28N2O2/c1-25-13-15(14-27-23(26)16-6-3-2-4-7-16)10-19-18-8-5-9-20-22(18)17(12-24-20)11-21(19)25/h5,8-10,12,15-16,21,24H,2-4,6-7,11,13-14H2,1H3/t15-,21-/m1/s1
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 0.661n/an/an/an/an/a



Freie Universit£t Berlin

Curated by ChEMBL


Assay Description
Partial agonism at 5-HT2A receptor was evaluated in presence of ketanserin (3-10 nM) in isolated rat tail artery


J Med Chem 42: 659-68 (1999)


Article DOI: 10.1021/jm981092u
BindingDB Entry DOI: 10.7270/Q21J9C0D
More data for this
Ligand-Target Pair