BDBM50411228 CHEMBL448457

SMILES Brc1cc(cnc1Br)N1CC[C@@H]2CN[C@@H]2C1

InChI Key InChIKey=VBSTVVDALUYNRL-GMSGAONNSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50411228   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50411228(CHEMBL448457)
Affinity DataEC50:  76nMAssay Description:Agonist activity at human alpha4beta2 ACHR expressed in HEK293 cells assessed as change in intracellular calcium concentration by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50411228(CHEMBL448457)
Affinity DataEC50:  110nMAssay Description:Agonist activity against human alpha3beta4 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Burnham Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50411228(CHEMBL448457)
Affinity DataEC50:  75.9nMAssay Description:Agonist activity against human alpha4beta2 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed