BDBM50411442 CHEMBL235579

SMILES Clc1ccc(O[C@H]2CCCNC2)cc1C(=O)NCC12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=VXFCQJMLQVJIKZ-UVLALUNPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50411442   

TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50411442(CHEMBL235579)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed