BDBM50414718 CHEMBL541223

SMILES [H][C@]12CC[C@@]([H])(CC(C1)NC(=O)c1cc3ccccc3n(C(C)C)c1=O)N2CCN(C)CCc1c[nH]c2ccccc12

InChI Key InChIKey=BNYAQKKSDCNZOB-SVBPBHIXSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414718   

Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50414718(CHEMBL541223)
Affinity DataKi:  39.8nMAssay Description:Displacement of [H]GR-113808 from human 5HT4C receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50414718(CHEMBL541223)
Affinity DataEC50:  1.26nMAssay Description:Agonist activity at human 5HT4C receptor expressed in HEK293 cells assessed as acumulation of cAMP by flash plate adenylyl cyclase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed