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BDBM50415141 CHEMBL576819

SMILES: Cc1ccccc1COC1=NCCN1

InChI Key: InChIKey=LGTDYALRCIBCMI-UHFFFAOYSA-N

Data: 3 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50415141   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-2B adrenergic receptor


(Homo sapiens (Human))
BDBM50415141
PNG
(CHEMBL576819)
Show SMILES Cc1ccccc1COC1=NCCN1
Show InChI InChI=1S/C11H14N2O/c1-9-4-2-3-5-10(9)8-14-11-12-6-7-13-11/h2-5H,6-8H2,1H3,(H,12,13)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
398n/an/an/an/an/an/an/an/a



Universita degli Studi di Camerino

Curated by ChEMBL


Assay Description
Displacement of [3H]RX821002 from human alpha2B adrenoceptor expressed in CHO cell membrane after 30 mins by liquid scintillation counting


J Med Chem 52: 7319-22 (2009)


Article DOI: 10.1021/jm901262f
BindingDB Entry DOI: 10.7270/Q2J104DZ
More data for this
Ligand-Target Pair
Alpha-2B adrenergic receptor


(Homo sapiens (Human))
BDBM50415141
PNG
(CHEMBL576819)
Show SMILES Cc1ccccc1COC1=NCCN1
Show InChI InChI=1S/C11H14N2O/c1-9-4-2-3-5-10(9)8-14-11-12-6-7-13-11/h2-5H,6-8H2,1H3,(H,12,13)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.51E+3n/an/an/an/a



Universita degli Studi di Camerino

Curated by ChEMBL


Assay Description
Agonist activity at human alpha2B adrenoceptor expressed in CHO cells assessed as extracellular acidification by cytosensor microphysiometry


J Med Chem 52: 7319-22 (2009)


Article DOI: 10.1021/jm901262f
BindingDB Entry DOI: 10.7270/Q2J104DZ
More data for this
Ligand-Target Pair
Alpha-2A adrenergic receptor


(Homo sapiens (Human))
BDBM50415141
PNG
(CHEMBL576819)
Show SMILES Cc1ccccc1COC1=NCCN1
Show InChI InChI=1S/C11H14N2O/c1-9-4-2-3-5-10(9)8-14-11-12-6-7-13-11/h2-5H,6-8H2,1H3,(H,12,13)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
35n/an/an/an/an/an/an/an/a



Universita degli Studi di Camerino

Curated by ChEMBL


Assay Description
Displacement of [3H]RX821002 from human alpha2A adrenoceptor expressed in CHO cell membrane after 30 mins by liquid scintillation counting


J Med Chem 52: 7319-22 (2009)


Article DOI: 10.1021/jm901262f
BindingDB Entry DOI: 10.7270/Q2J104DZ
More data for this
Ligand-Target Pair
Alpha-2C adrenergic receptor


(Homo sapiens (Human))
BDBM50415141
PNG
(CHEMBL576819)
Show SMILES Cc1ccccc1COC1=NCCN1
Show InChI InChI=1S/C11H14N2O/c1-9-4-2-3-5-10(9)8-14-11-12-6-7-13-11/h2-5H,6-8H2,1H3,(H,12,13)
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
501n/an/an/an/an/an/an/an/a



Universita degli Studi di Camerino

Curated by ChEMBL


Assay Description
Displacement of [3H]RX821002 from human Alpha-2C adrenoceptor expressed in CHO cell membrane after 30 mins by liquid scintillation counting


J Med Chem 52: 7319-22 (2009)


Article DOI: 10.1021/jm901262f
BindingDB Entry DOI: 10.7270/Q2J104DZ
More data for this
Ligand-Target Pair
Alpha-2C adrenergic receptor


(Homo sapiens (Human))
BDBM50415141
PNG
(CHEMBL576819)
Show SMILES Cc1ccccc1COC1=NCCN1
Show InChI InChI=1S/C11H14N2O/c1-9-4-2-3-5-10(9)8-14-11-12-6-7-13-11/h2-5H,6-8H2,1H3,(H,12,13)
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.88E+3n/an/an/an/a



Universita degli Studi di Camerino

Curated by ChEMBL


Assay Description
Agonist activity at human Alpha-2C adrenoceptor expressed in CHO cells assessed as extracellular acidification by cytosensor microphysiometry


J Med Chem 52: 7319-22 (2009)


Article DOI: 10.1021/jm901262f
BindingDB Entry DOI: 10.7270/Q2J104DZ
More data for this
Ligand-Target Pair