BDBM50416873 CHEMBL1257454
SMILES COc1ccc(F)cc1C(C)(C)CC(O)(CNc1cccc2nc(C)ccc12)C(F)(F)F
InChI Key InChIKey=OUFQSIUBFDHEQY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50416873
Affinity DataIC50: 25.1nMAssay Description:Transrepression activity at glucocorticoid receptor-mediated antiinflammatory activity in human THP1 cells assessed as inhibition of LPS-induced IL-8...More data for this Ligand-Target Pair
Affinity DataEC50: 25.1nMAssay Description:Transactivation activity at glucocorticoid receptor in human HeLa cells assessed as induction of MMTV promoter activity by luciferase reporter gene a...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human recombinant progesterone receptor expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Transrepression activity at glucocorticoid receptor-mediated antiinflammatory activity in human HeLa cells assessed as inhibition of TPA-induced coll...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human recombinant mineralocorticoid receptor expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human recombinant androgen receptor expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Binding affinity to human recombinant glucocorticoid receptor expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair