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BDBM50417069 CHEMBL1234889

SMILES: FC(F)(F)c1nn(CC(=O)Nc2sc3CCCCc3c2C(=O)N[C@@H]2CCNC2)c2CCCCc12

InChI Key: InChIKey=CFYCEUGQUDABFL-UGPWUYPHNA-N

Data: 1 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417069   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50417069
PNG
(CHEMBL1234889)
Show SMILES FC(F)(F)c1nn(CC(=O)Nc2sc3CCCCc3c2C(=O)N[C@@H]2CCNC2)c2CCCCc12
Show InChI InChI=1/C23H28F3N5O2S/c24-23(25,26)20-14-5-1-3-7-16(14)31(30-20)12-18(32)29-22-19(15-6-2-4-8-17(15)34-22)21(33)28-13-9-10-27-11-13/h13,27H,1-12H2,(H,28,33)(H,29,32)/t13-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/an/an/a 251n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Positive modulation of GluR1


Bioorg Med Chem Lett 20: 6072-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.063
BindingDB Entry DOI: 10.7270/Q2930VFM
More data for this
Ligand-Target Pair