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BDBM50417077 CHEMBL1257181

SMILES: CCN(CC)Cc1cn(CC(=O)Nc2sc3CCCCc3c2C(N)=O)nc1C(F)(F)F

InChI Key: InChIKey=MEXAIEAJJBGPIW-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417077   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50417077
PNG
(CHEMBL1257181)
Show SMILES CCN(CC)Cc1cn(CC(=O)Nc2sc3CCCCc3c2C(N)=O)nc1C(F)(F)F
Show InChI InChI=1S/C20H26F3N5O2S/c1-3-27(4-2)9-12-10-28(26-17(12)20(21,22)23)11-15(29)25-19-16(18(24)30)13-7-5-6-8-14(13)31-19/h10H,3-9,11H2,1-2H3,(H2,24,30)(H,25,29)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 631n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Positive modulation of GluR1


Bioorg Med Chem Lett 20: 6072-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.063
BindingDB Entry DOI: 10.7270/Q2930VFM
More data for this
Ligand-Target Pair