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BDBM50417078 CHEMBL1258914

SMILES: NC(=O)c1c(NC(=O)Cn2cc(CNC3CC3)c(n2)C(F)(F)F)sc2CCCCc12

InChI Key: InChIKey=JGHBPNBQOJRAQU-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417078   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50417078
PNG
(CHEMBL1258914)
Show SMILES NC(=O)c1c(NC(=O)Cn2cc(CNC3CC3)c(n2)C(F)(F)F)sc2CCCCc12
Show InChI InChI=1S/C19H22F3N5O2S/c20-19(21,22)16-10(7-24-11-5-6-11)8-27(26-16)9-14(28)25-18-15(17(23)29)12-3-1-2-4-13(12)30-18/h8,11,24H,1-7,9H2,(H2,23,29)(H,25,28)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 631n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Positive modulation of GluR1


Bioorg Med Chem Lett 20: 6072-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.063
BindingDB Entry DOI: 10.7270/Q2930VFM
More data for this
Ligand-Target Pair