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BDBM50417157 CHEMBL1270607

SMILES: Fc1ccc(cc1)C(=O)OCC#CCSc1nnc(o1)-c1ccccc1Cl

InChI Key: InChIKey=JMXMKJYVWONUML-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417157   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 15-lipoxygenase


(Homo sapiens (Human))
BDBM50417157
PNG
(CHEMBL1270607)
Show SMILES Fc1ccc(cc1)C(=O)OCC#CCSc1nnc(o1)-c1ccccc1Cl
Show InChI InChI=1S/C19H12ClFN2O3S/c20-16-6-2-1-5-15(16)17-22-23-19(26-17)27-12-4-3-11-25-18(24)13-7-9-14(21)10-8-13/h1-2,5-10H,11-12H2
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PC sid
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Similars

Article
PubMed
57n/an/an/an/an/an/an/an/a



National Human Genome Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human N-terminal His6-tagged reticulocyte 15-lipoxygenase-1 catalytic site assessed as 15-HPETE formation by Michaelis-Menten equation ...


J Med Chem 53: 7392-404 (2010)


Article DOI: 10.1021/jm1008852
BindingDB Entry DOI: 10.7270/Q2SJ1KVW
More data for this
Ligand-Target Pair