BDBM50417556 CHEMBL1230591

SMILES: CC(C)S(=O)(=O)N[C@H]1Cc2ccc(Cc3ccc(o3)C(F)(F)F)cc2C1

InChI Key: InChIKey=LONAEEDHLGMMRS-GGYSOQFKNA-N

Data: 1 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417556   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GRIA2 (Homo sapiens (Human))	BDBM50417556 (CHEMBL1230591) Show SMILES CC(C)S(=O)(=O)N[C@H]1Cc2ccc(Cc3ccc(o3)C(F)(F)F)cc2C1 Show InChI InChI=1/C18H20F3NO3S/c1-11(2)26(23,24)22-15-9-13-4-3-12(7-14(13)10-15)8-16-5-6-17(25-16)18(19,20)21/h3-7,11,15,22H,8-10H2,1-2H3/t15-/s2	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Modulatory activity at GluA2 receptor LBD				Bioorg Med Chem Lett 21: 805-11 (2011) Article DOI: 10.1016/j.bmcl.2010.11.098 BindingDB Entry DOI: 10.7270/Q2Q52QWZ
					More data for this Ligand-Target Pair				3D Structure (crystal)