BDBM50417668 CHEMBL1643368
SMILES Nc1nccc2cc(O[C@H]3CCCNC3)ccc12
InChI Key InChIKey=YHTZIHUTLKKYNH-LBPRGKRZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50417668
Affinity DataKi: 37.1nMAssay Description:Binding affinity to ROCK1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd
Curated by ChEMBL
Msd
Curated by ChEMBL
Affinity DataKi: 2.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair