BDBM50419652 MILVETEROL

SMILES O[C@@H](CNCCc1ccc(NC[C@H](O)c2ccccc2)cc1)c1ccc(O)c(NC=O)c1

InChI Key InChIKey=BMKINZUHKYLSKI-DQEYMECFSA-N

Data  3 KI  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50419652   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50419652(MILVETEROL)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]dihydroalprenolol from human beta2 adrenergic receptor expressing cell membrane by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50419652(MILVETEROL)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50419652(MILVETEROL)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50419652(MILVETEROL)
Affinity DataEC50:  0.501nMAssay Description:Agonist activity at human beta2 adrenergic receptor in human BEAS-2B cells by cAMP accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50419652(MILVETEROL)
Affinity DataEC50:  25nMAssay Description:Agonist activity at recombinant human beta1-adrenoceptor expressed in whole cells assessed as cAMP accumulation by homogeneous radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
Theravance

Curated by ChEMBL
LigandPNGBDBM50419652(MILVETEROL)
Affinity DataEC50:  0.0501nMAssay Description:Agonist activity at beta2 receptor in guinea pig trachea assessed as fast onset of inhibition of electrically stimulated contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50419652(MILVETEROL)
Affinity DataEC50:  0.0631nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in cells by cAMP accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50419652(MILVETEROL)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human beta3 adrenergic receptor expressed in cells by cAMP accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50419652(MILVETEROL)
Affinity DataEC50:  0.0631nMAssay Description:Agonist activity at recombinant human beta2-adrenoceptor expressed in whole cells assessed as cAMP accumulation by homogeneous radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50419652(MILVETEROL)
Affinity DataEC50:  0.0631nMAssay Description:Agonist activity at human recombinant beta2 receptor assessed as cAMP accumulation by radioimmunoassay and cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50419652(MILVETEROL)
Affinity DataEC50:  0.501nMAssay Description:Agonist activity at beta2-adrenoceptor endogenously expressed in human BEAS-2B cells assessed as cAMP accumulation by homogeneous radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50419652(MILVETEROL)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human beta1 adrenergic receptor expressed in cells by cAMP accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed