BDBM50419680 CHEMBL1945039

SMILES COc1ccccc1CNCc1cccc(CCNC[C@H](O)c2ccc(O)c3[nH]c(=O)sc23)c1

InChI Key InChIKey=VKCKAMBPNXKGHL-QFIPXVFZSA-N

Data  4 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50419680   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50419680(CHEMBL1945039)
Affinity DataIC50:  6.30nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50419680(CHEMBL1945039)
Affinity DataEC50:  126nMAssay Description:Binding affinity to Alpha-1D adrenoreceptor expressed in HEK cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50419680(CHEMBL1945039)
Affinity DataIC50:  50nMAssay Description:Displacement of radiolabeled iodocyanopindolol from beta1 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50419680(CHEMBL1945039)
Affinity DataEC50:  251nMAssay Description:Binding affinity to dopamine D2 receptor expressed in HEK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50419680(CHEMBL1945039)
Affinity DataIC50:  200nMAssay Description:Binding affinity to Alpha-1D adrenoceptor expressed in HEK cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50419680(CHEMBL1945039)
Affinity DataIC50:  1.00E+3nMAssay Description:Binding affinity to dopamine D2 receptor expressed in HEK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50419680(CHEMBL1945039)
Affinity DataEC50:  0.501nMAssay Description:Agonist activity at beta2 adrenoceptor in guinea pig trachea assessed as reduction in methacholine-induced contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50419680(CHEMBL1945039)
Affinity DataEC50:  63nMAssay Description:Binding affinity to beta1 adrenoceptor expressed in CHO cells by cAMP accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50419680(CHEMBL1945039)
Affinity DataEC50:  0.631nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in H292 cells assessed as increase in cAMP accumulation after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed