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BDBM50420190 5052::ACETYLCYSTEINE

SMILES: CC(=O)N[C@@H](CS)C(O)=O

InChI Key: InChIKey=PWKSKIMOESPYIA-BYPYZUCNSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50420190   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Solute carrier family 22 member 6


(Rattus norvegicus)
BDBM50420190
PNG
(5052 | ACETYLCYSTEINE)
Show SMILES CC(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
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MMDB
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.00E+6n/an/an/an/an/an/an/an/a



University of Rochester School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes


Mol Pharmacol 62: 921-6 (2002)


Article DOI: 10.1124/mol.62.4.921
BindingDB Entry DOI: 10.7270/Q2Z320X6
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50420190
PNG
(5052 | ACETYLCYSTEINE)
Show SMILES CC(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

DrugBank
MMDB
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.16E+6n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human LoVo/DX cells using Boc-Lys(Ac)-AMC as substrate assessed as release of AMC pre-incubated for 15 mins followed by substra...


Bioorg Med Chem Lett 26: 667-71 (2016)


Article DOI: 10.1016/j.bmcl.2015.11.045
BindingDB Entry DOI: 10.7270/Q2D220G2
More data for this
Ligand-Target Pair