BDBM50420298 CHEMBL2089033

SMILES CC(C)n1cnc2c(NCc3ccc(cc3)-c3ccccn3)nc(N[C@@H]3CCC[C@H](O)[C@@H]3O)nc12

InChI Key InChIKey=UVOREYMEAFPJPX-FUPPJEDESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50420298   

TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420298(CHEMBL2089033)
Affinity DataIC50:  270nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50420298(CHEMBL2089033)
Affinity DataIC50:  890nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420298(CHEMBL2089033)
Affinity DataIC50:  600nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420298(CHEMBL2089033)
Affinity DataIC50:  370nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed