BDBM50421182 CHEMBL2086797

SMILES CC[C@H](C)[C@H](NC(=O)CN1C\C=C/CCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(O)=O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(N)=O

InChI Key InChIKey=RVFTWZXOLYRPQN-NEMAPAQASA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50421182   

TargetGTPase HRas(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50421182(CHEMBL2086797)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to His6-tagged HRas expressed in Escherichia coli (BL21) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSon of sevenless homolog 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50421182(CHEMBL2086797)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition to His6-tagged Sos1 catalytic domain-mediated nucleotide exchange by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50421182(CHEMBL2086797)
Affinity DataKd:  1.58E+5nMAssay Description:Binding affinity to His6-tagged HRas-GDP expressed in Escherichia coli (BL21) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed