BDBM50421763 CHEMBL2364562
SMILES NC(=O)c1csc(n1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@H](O)[C@@H]1O
InChI Key InChIKey=INQLNSVYIFCUML-YYKMIFDDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50421763
Affinity DataKi: 240nMAssay Description:Compound was tested for inhibitory activity against Inosine-5'-monophosphate dehydrogenase, the type of inhibition in not competitiveMore data for this Ligand-Target Pair
Affinity DataKi: 430nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataKi: 470nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
Affinity DataKi: 710nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
TargetGlutamate dehydrogenase 1, mitochondrial(Bos taurus)
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKi: 4.50E+3nMAssay Description:In vitro inhibitory activity against bovine liver glutamate dehydrogenase (GDH)More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase B chain(Sus scrofa)
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKi: 2.52E+4nMAssay Description:In vitro inhibitory activity against pig heart lactate dehydrogenase (LDH)More data for this Ligand-Target Pair
TargetAlcohol dehydrogenase E/S chain(Equus caballus)
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKi: 2.65E+4nMAssay Description:In vitro inhibitory activity against horse liver Alcohol dehydrogenase (ADH)More data for this Ligand-Target Pair
TargetMalate dehydrogenase, cytoplasmic(Sus scrofa (pig))
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKi: 3.63E+4nMAssay Description:In vitro inhibitory activity against pig heart cytoplasmic malate dehydrogenase (MDH)More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
TargetAlcohol dehydrogenase E/S chain(Equus caballus)
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKd: 2.70E+4nMAssay Description:Dissociation constant from Alcohol dehydrogenaseMore data for this Ligand-Target Pair