BDBM50422041 GECLOSPORIN

SMILES CCC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C

InChI Key InChIKey=ZMKGDQSIRSGUDJ-VSROPUKISA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50422041   

TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Sandoz Pharma

Curated by ChEMBL
LigandPNGBDBM50422041(GECLOSPORIN)
Affinity DataIC50:  310nMAssay Description:In vitro binding affinity of the compound against cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Sandoz Pharma

Curated by ChEMBL
LigandPNGBDBM50422041(GECLOSPORIN)
Affinity DataIC50:  310nMAssay Description:In vitro binding affinity of the compound against cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-2(Mus musculus)
Sandoz Pharma

Curated by ChEMBL
LigandPNGBDBM50422041(GECLOSPORIN)
Affinity DataIC50:  13nMAssay Description:The compound was evaluated in vitro for the immunosuppressive activity in interleukin-2 by interleukin-2 reporter gene assay (IL2-RGA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed