BDBM50424960 CHEMBL2316155::US9409845, Table 1, Compound 16: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(3-hydroxyl-4-methoxybenzylidene)cyclohexanone

SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(OC)c(O)c3)C2=O)c1

InChI Key InChIKey=CNMLPAQHCYHPBA-BEQMOXJMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424960   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424960(CHEMBL2316155 | US9409845, Table 1, Compound 16: (...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424960(CHEMBL2316155 | US9409845, Table 1, Compound 16: (...)
Affinity DataIC50:  5.37E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In DepthDetails US Patent